FIELD: chemistry.
SUBSTANCE: disclosed is a method of producing a porous ceramic from hydroxyapatite having antimicrobial activity for use in reconstructive surgery and dentistry when restoring bone defects. The method involves synthesis of a zinc-, copper-, iron- or silver-substituted hydroxyapatite from calcium oxide and disubstituted ammonium phosphate in the presence of zinc, copper, iron or silver nitrate, taken in amount of 0.5-10 mol % with respect to calcium oxide using mechanochemical activation and subsequent preparation of ceramic slip from the obtained powder and polyacrylamide gel. Polyurethane sponges with porosity of 50-90 vol. % are soaked with the obtained slip and then sintered at temperature of 900-1200°C.
EFFECT: obtaining single-phase porous ceramic with antimicrobial activity.
2 cl, 5 ex, 4 dwg
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