FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to pharmaceutics and medicine and concerns a method for making a composite of collagen and nanohydroxyapatite for bone tissue defect repair by mixing restructured collagen and aqueous glucose, keeping at room temperature to swelling and heating to 35-45°C; the prepared suspension is homogenised and added with a nanohydroxyapatite suspension in aqueous glucose at weight proportions of collagen to nanohydroxyapatite 5:1 to 1:5; it is followed by homogenising and sterilising the prepared composite for bone tissue defect repair to be used in bone tissue defect repair.
EFFECT: material has a distinct architecture close to a native analogue, and possesses high mechanical strength.
7 cl, 4 dwg, 1 ex
Title | Year | Author | Number |
---|---|---|---|
METHOD FOR HYDROXYAPATITE-COLLAGENE COMPOSITE PRODUCTION | 2016 |
|
RU2631594C1 |
BIOCOMPOSITE OSTEOPLASTIC MATERIAL TO ACCELERATE THE CONSOLIDATION OF ANIMAL FRACTURES | 2022 |
|
RU2805654C1 |
MEDICAL ADHESIVE BIOIMPLANT OF NEW GENERATION OF BIOPOLYMER NANOCOMPOSITES IN FORM OF SEMI-SYNTHETIC POLYMER MATRIX WITH USE OF LASER PROCESSING | 2011 |
|
RU2477996C1 |
BIOABSORBABLE COLLAGEN MATRIX, METHOD OF PRODUCTION AND APPLICATION | 2007 |
|
RU2353397C2 |
NEXT GENERATION MEDICAL BIOLOGICAL ADHESIVE BASED ON BIOPOLYMER COMPOSITES AS SEMISYNTHETIC POLYMER MATRIXES WITH USING LASER TECHNOLOGIES | 2013 |
|
RU2543321C2 |
BIOACTIVE COMPOSITE MATERIAL FOR BONE DEFECT REPLACEMENT AND METHOD FOR ITS MANUFACTURE | 2016 |
|
RU2617050C1 |
IMPLANTS FOR REPLACEMENT "LOAD-BEARING" BONES HAVING HIERARCHICALLY ORGANISED ARCHITECTURE OBTAINED THROUGH TRANSFORMATION OF PLANT STRUCTURES | 2011 |
|
RU2585958C2 |
COMPOSITION OF BIORESORBABLE 3D MATRIX FOR RESTORING BONE TISSUE DEFECTS | 2021 |
|
RU2762511C1 |
OSTEOINDUCING MATERIAL (VARIANTS) | 2006 |
|
RU2317088C1 |
BIOACTIVE COATING FOR BONE TISSUE RECOVERY | 2019 |
|
RU2717676C1 |
Authors
Dates
2013-02-27—Published
2012-02-16—Filed