FIELD: medicine.
SUBSTANCE: invention describes a method for assessing the copper nanoparticles administration safety consisting in measuring caspase-3 antigen expression in microglial cells of the cortical sensorimotor area after copper nanoparticles introduction in comparison with control animals by caspase-3 expressing microglial cell count per a standard area unit of the identical sensorimotor areas.
EFFECT: method enables determining a tolerance of the preparation to be administered, specifying target organs, choosing the most adequate administration route.
2 cl, 5 ex, 6 tbl, 12 dwg
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Authors
Dates
2013-03-10—Published
2011-05-17—Filed