COMPOUNDS OF HYPERBRANCHED POLYMER Boltorn H COMPLEXES POSSESSING ANTI-CANDIDA ACTIVITY AND METHOD FOR PREPARING THEM Russian patent published in 2013 - IPC C08G63/02 A61P31/10 A61K31/765 

FIELD: medicine.

SUBSTANCE: invention refers to compounds of hyperbranched polymer Boltorn H complexes which may be used as substances, bases, ingredients and other biologically active substances in preparing chemopreparations for treating and preventing human fungoid diseases, particularly Candida mycosis, as well as to a method for preparing said compounds. The compounds of hyperbranched polymer Boltorn H complexes contains 10 to 14 groups of propionic or acrylic acids and 10 to 14 metal ions. The given compounds possess anti-candida activity on Candida albicans, Candida krusei, Candida tropicalis, Candida parapsilosis and provides action on the Candida proteinase system and the cell wall components. The method for preparing said compounds consists in synthesis of the compounds containing 10 to 14 groups of propionic or acrylic acids and 10 to 14 metal ions with the use of consecutive reactions of etherification, substitution and addition.

EFFECT: higher preventive and clinical effectiveness in the disease.

2 cl, 3 tbl, 5 dwg