METHOD OF PRODUCING 1-(2-METHYL-1,4-PHENOXYPHENYL)-BUTANE-1,3-DIONE Russian patent published in 2013 - IPC C07C49/84 C07C45/45 

Abstract RU 2478606 C1

FIELD: chemistry.

SUBSTANCE: invention relates to a method of producing 1-(2-methyl-4-phenoxyphenyl)-butane-1,3-dione of formula which can be used as a synthon in synthesis of biologically active substances. The method involves reaction of 1-(2-methyl-4-phenoxyphenyl)-ethanone with ethyl acetate in the presence of potassium tert-butoxide in a medium of absolute N,N'-dimethylformamide at temperature of 50-52°C in a nitrogen atmosphere with molar ratio of 1-(2-methyl-4-phenoxyphenyl)-ethanone to ethyl acetate of 1:1.5.

EFFECT: invention enables to obtain the end product using a simple method in a single step.

2 ex

Similar patents RU2478606C1

Title Year Author Number
3-PHENOXYPHENYL-CONTAINING 1,3-DIKETONES AS STARTING COMPOUNDS FOR PRODUCING CHELATE COMPLEXES THEREOF WITH COPPER (II) IONS AND METHOD OF PRODUCING 3-PHENOXYPHENYL-CONTAINING 1,3-DIKETONES 2012
  • Popov Jurij Vasil'Evich
  • Korchagina Tat'Jana Konstantinovna
  • Kalmykova Galina Viktorovna
RU2475473C1
METHOD OF PRODUCING 1-(3-PHENOXYPHENYL)BUTANE-1,3-DIONE 2013
  • Popov Jurij Vasil'Evich
  • Korchagina Tat'Jana Konstantinovna
  • Kalmykova Galina Viktorovna
  • Losevskaja Lilija Aleksandrovna
RU2529029C1
APPLICATION OF CHIRAL ARYLKETONES FOR NEUTROPHIL-DEPENDENT INFLAMMATORY DISEASES 2003
  • Allegretti Marchello
  • Bertini Rikkardo
  • Chesta Marija Kandida
  • Bitstsarri Chintsija
  • Kolotta Franchesko
RU2345759C2
METHOD OF PRODUCING Α-DIAZOCARBONYL COMPOUNDS IN AQUEOUS MEDIUM 2018
  • Krasavin Mikhail Yurevich
  • Darin Dmitrij Viktorovich
  • Kantin Grigorij Pavlovich
RU2686489C1
TRIAZOLO (4,3-a) 1,4 BENZO DIAZEPINES AND THRENO (3,2 1992
  • Armin Valzer[Ch]
RU2094436C1
METHOD OF SYNTHESIS OF TRIAZOLO-[4,3-A]-[1,4]-DIAZEPINES 1988
  • Armin Valzer[Ch]
RU2071962C1
HYDROXYPURINE COMPOUNDS AND WAYS OF THEIR USE 2015
  • U Linyun
  • Lun Chaofen
  • Chzhan Pen
  • Chen Syaosin
  • Chzhan Li
  • Lyu Chzhovej
  • Li Tszyan
  • Chen Shukhuej
RU2673458C1
DIARYL ETHERS, METHOD FOR THEIR OBTAINING AND DIARYL ETHERS-CONTAINING HERBICIDE COMPOSITIONS, INTERMEDIATE COMPOUNDS, METHOD FOR THEIR OBTAINING, METHOD TO PROTECT AGAINST WEEDS AND METHOD OF PLANT DESICCATION 1998
  • Pulman Dehvid A.
  • Jing Baj-Ping
  • Vu Shao-Jong
  • Gupta Sandip
  • Simokharada Khirosi
  • Tsukamoto Masamitsu
RU2180336C2
METHOD OF PRODUCING ETHYL 5-METHYL-3-(3-PHENOXYPHENYL)-1-PHENYL-1H-PYRAZOLYL-4-CARBOXYLATE 2015
  • Popov Jurij Vasilevich
  • Korchagina Tatjana Konstantinovna
  • Lobasenko Viktorija Safiullovna
  • Efremova Olga Sergeevna
RU2582127C1
METHOD FOR PREPARING BICYCLIC DIKETONE SALTS AND INTERMEDIATE COMPOUND 2003
  • Shnajder German
  • Ljuti Kristof
RU2315743C2

RU 2 478 606 C1

Authors

Popov Jurij Vasil'Evich

Korchagina Tat'Jana Konstantinovna

Kalmykova Galina Viktorovna

Shinkarenko Ekaterina Arkad'Evna

Dates

2013-04-10Published

2012-02-07Filed