CRYSTALLINE FORMS OF TIGECYCLINE AND METHOD FOR PREPARING THEM Russian patent published in 2013 - IPC C07C237/26 C07C231/24 A61K31/65 A61P31/00 

Abstract RU 2478612 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to a crystalline form of tigecycline I characterised by the fact that an X-ray picture formed by powder X-ray diffraction shows diffraction peaks at the angles of 2θ 5.2° and 11.1°, as well as a diffraction peak at the angle of 29 8.3° and a diffraction peak at the angle of 2θ 24.8°. The crystalline form of tigecycline I is used for preparing pharmaceutical formulations, for treating bacterial diseases.

EFFECT: preparing the solid crystalline form of tigecycline possessing the improved stability characteristics.

8 cl, 9 dwg, 4 tbl, 10 ex

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RU 2 478 612 C2

Authors

Krishnan Lalita

Deshmukh Sabodkh S.

Khadfild Ehntoni

Khuang Dzhejms V.

Ku Manching Sherri

Dates

2013-04-10Published

2006-05-25Filed