FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to organic chemistry, particularly a method for preparing (1,5,3-ditiazepinan-3-yl)(thio)phenols of general formula (1) which consists in the fact that amino(thio)phenols (o-aminophenol, n-aminophenol, n-aminothiophenol) react with 1,3,6-oxaditiapinane in the presence of the catalyst Sm(NO3)3·6H2O in the molar ration of amino(thio)phenol : 1,3,6-oxaditiapinane : Sm(NO3)3·6H2O = 10 : 10 : (0.3-0.7) in the solvents of chloroform-ethanol (in volume ratio 1:1) in the argon environment for 2.5-3.5 h.
EFFECT: what is developed is a method for preparing new (1,5,3-ditiazepinan-3-yl)(thio)phenols which can find application as antibacterial, antimycotic and antiviral agents as biologically active complexing agents, selective sorbents and extractants of precious metals, special agents for bacterial activity suppression in various technical media.
1 cl, 1 tbl, 1 ex
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Authors
Dates
2013-04-10—Published
2011-05-30—Filed