METHOD FOR PREPARING (1,5,3-DITIAZEPINAN-3-YL)(THIO)PHENOLS Russian patent published in 2013 - IPC C07D285/36 

Abstract RU 2478623 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to organic chemistry, particularly a method for preparing (1,5,3-ditiazepinan-3-yl)(thio)phenols of general formula (1) which consists in the fact that amino(thio)phenols (o-aminophenol, n-aminophenol, n-aminothiophenol) react with 1,3,6-oxaditiapinane in the presence of the catalyst Sm(NO3)3·6H2O in the molar ration of amino(thio)phenol : 1,3,6-oxaditiapinane : Sm(NO3)3·6H2O = 10 : 10 : (0.3-0.7) in the solvents of chloroform-ethanol (in volume ratio 1:1) in the argon environment for 2.5-3.5 h.

EFFECT: what is developed is a method for preparing new (1,5,3-ditiazepinan-3-yl)(thio)phenols which can find application as antibacterial, antimycotic and antiviral agents as biologically active complexing agents, selective sorbents and extractants of precious metals, special agents for bacterial activity suppression in various technical media.

1 cl, 1 tbl, 1 ex

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RU 2 478 623 C2

Authors

Dzhemilev Usein Memetovich

Rakhimova Elena Borisovna

Vasil'Eva Inna Vladimirovna

Tuljabaev Artur Radisovich

Ibragimov Askhat Gabdrakhmanovich

Dates

2013-04-10Published

2011-05-30Filed