FIELD: chemistry.
SUBSTANCE: invention relates to a method of producing N,N'-bis(β-piperazinoethyl)-2-aryl(alkyl)imidazolidines, which involves reaction of 60-80% aqueous solution of N,N'-bis(piperazinoethyl)ethylenediamine(hexamine) with an aromatic or aliphatic aldehyde at temperature of 100-120°C for 1-1.5 hours, and then at 175-185°C for 2-2.5 hours with distillation of water, wherein the molar ratio of hexamine to the aromatic or aliphatic aldehyde is 1:(1.1-1.3). The aldehyde used can be benzoic or salicylic or butyric or isobutyric aldehyde.
EFFECT: safety of the synthesis method and high output of the end product.
4 cl, 6 ex
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Authors
Dates
2013-04-20—Published
2012-03-16—Filed