FIELD: medicine.
SUBSTANCE: with underlying integrated treatment including therapeutic diet composition and physical hyperactivity, morning urine is examined by ELISA for the concentration of the major metabolite melatonin 6-sulphatoxymelatonin, and if the value of the latter is 32.4 ng/ml and more, the presence of sleep disturbances is predicted, a sleep efficiency index is calculated, and its value 90.8% and lower requires correction by the preparation mebicar (Adaptol) 1.0 g in 2 separate doses; the therapeutic course is 2 months.
EFFECT: method enables preventing developing metabolic complications, reducing the drug-induced load, reducing length of treatment and improving the quality of sleep due to predicted disturbances during the initial admission to endocrinology department.
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