PYRIDYLOXY DERIVATIVES EFFECTIVE AS PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR) GAMMA ACTIVATOR/MODULATOR Russian patent published in 2013 - IPC C07D401/12 A61K31/4439 A61P3/04 A61P3/06 A61P3/10 A61P29/00 A61P35/00 A61P35/02 

Abstract RU 2480463 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to novel pyridyloxy derivatives or its pharmaceutically acceptable ester or a pharmaceutically acceptable salt of the mentioned derivatice or ester of general formula (I), wherein R represents a pyridyl group substituted by 1-3 groups independently specified in a group of substitutes A; the group of substitutes A represents a group comprising halogen atom, C1-C6 alkyl group and C1-C6 alkoxy group, and Me represents a methyl group. Also, the invention refers to specific compounds of formula (I), to a pharmaceutical composition and a receptor-γ activator/modulator on the basis of a compound of formula (I), to a method of treating and/or preventing a disease.

EFFECT: there are prepared novel pyridyloxy derivatives effective in treating the disease mediated by peroxisome proliferator activated receptor-γ (PPAR) γ.

37 cl, 2 tbl, 21 ex

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RU 2 480 463 C1

Authors

Sinozuka Tsuesi

Tsukada Tomokharu

Fudzii Kunikhiko

Mori Makoto

Dates

2013-04-27Published

2010-03-03Filed