BENZIMIDAZOLE DERIVATIVE Russian patent published in 2011 - IPC C07D405/14 C07D493/10 A61K31/4439 A61P1/04 

FIELD: chemistry.

SUBSTANCE: compound has general formula (where R¹ and R³ are identical or different, and each denotes a hydrogen atom or C1-6alkyl; R² denotes, for example, 5,5-dimethyl-1,3-dioxan-2-yl, 5,7-dioxaspiro[2.5]oct-6-yl, 1,5,9-trioxaspiro [5.5]undec-3-yl, 2,2-dimethyl-1,3-dioxan-5-yl etc; R⁴, R⁵, R⁶ and R⁷ each denotes a hydrogen atom, a halogen atom, C1-6 alkyl, C1-6 halogenalkyl, C1-6 alkoxy, C1-6 halogenalkoxy etc, and W¹ denotes a single bond, methylene or ethylene, or salt thereof.

EFFECT: compound has excellent inhibiting activity towards secretion of gastric hydrochloric acid and more effectively in preserving inhibiting activity towards secretion of gastric hydrochloric acid, can maintain pH in the stomach for a long period of time, is safe and has acceptable physical and chemical resistance.

40 cl, 4 tbl, 97 ex