FIELD: medicine.
SUBSTANCE: multiple (4-6 times) saliva and faeces samples are taken in critical months (February to March, September to October). The heated samples (100°C, 20 min) are tested for Helicobacter pylori O-antigen, while the non-heated samples are tested for VacA-antigen by coagglutination reaction on a slide and trays, respectively. It is followed by determining a frequency of these antigens, and a high O-antigen frequency (≥50%) and a low VacA-antigen frequency (≤40%) enable to consider a risk of exacerbations (dyspepsia, gastritis, peptic ulcer) to be probable, and the value of VacA-antigen ≤25% shows a high risk of an exacerbation.
EFFECT: invention enables optimising a diagnosis and ensuring timely prevention of exacerbations of helicobacteriosis, evaluating the effectiveness of an eradication therapy.
1 dwg, 1 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PROBABILITY DETERMINATION OF BECOMING INFECTED WITH HELICOBACTER PYLORI | 2007 |
|
RU2360251C1 |
| METHOD FOR PREDICTION OF INCIDENCE OF Helicobacter pylori ANTIGENS FOR PERIOD FROM 2013 TO 2019 | 2012 |
|
RU2536018C2 |
| METHOD FOR PREPARING TEST-SYSTEM FOR DETERMINATION OF HELICOBACTER PYLORI CYTOTOXIN-ASSOCIATED PROTEIN ANTIGENS IN BIOLOGICAL MATERIAL IN INFECTED PATIENTS BY CO-AGGLUTINATION REACTION | 2002 |
|
RU2232989C1 |
| METHOD OF PREPARING DIAGNOSTICUM FOR DETECTION OF HELICOBACTER PYLOPI ANTIGEN IN COAGGLUTINATION REACTION | 2000 |
|
RU2186394C2 |
| NONINVASIVE METHOD FOR REVEALING HELICOBACTER PYLORI AT ULCEROUS DUODENAL DISEASE | 2000 |
|
RU2193203C2 |
| METHOD OF PREPARING DIAGNOSTICUM FOR DETECTION OF CAMPYLOBACTER THERMOSTABLE ANTIGENS | 1996 |
|
RU2086984C1 |
| METHOD OF PREDICTING RISK OF DEVELOPMENT OF DESTRUCTIVE CHANGES OF GASTRODUODENTAL ZONE MUCOUS TUNIC | 2008 |
|
RU2391915C1 |
| METHOD OF TREATING Helicobacter pylori ASSOCIATED CHRONIC ULCEROUS DISEASE OF STOMACH AND DUODENUM | 2010 |
|
RU2416408C1 |
| DIAGNOSTIC TECHNIQUE FOR DEGREE OF ACTIVITY OF ANTRAL HELICOBACTER-ASSOCIATED GASTRITIS IN PATIENTS WITH BRONCHIAL ASTHMA | 2009 |
|
RU2394499C1 |
| METHOD OF EVALUATION OF REACTIVITY AND IMMUNOLOGICAL SAFETY OF VACCINE | 1995 |
|
RU2086983C1 |
