METHOD FOR PREDICTION OF INCIDENCE OF Helicobacter pylori ANTIGENS FOR PERIOD FROM 2013 TO 2019 Russian patent published in 2014 - IPC G01N33/554 

FIELD: medicine.

SUBSTANCE: estimating a probability of the Helicobacter pylori infection is ensured by taking a biomaterial (K₄), diagnosing a gastrointestinal disease (K₃), age (K₁) and H.pylori O-antigen (O_ag) in the biomaterial by the co-agglutination reaction followed by deriving a coefficient (K₂) depending on the current calendar year; thereafter, PI_O is calculated by formula PI_O= SF×K₁×K₂×K₃×K₄, wherein SF, a seasonal fluctuation, makes 50 in the first month of the year, 61 in the 2^nd, 55 in the 3^rd, 31 in the 4^th, 28 in the 5^th, 14 in the 6^th, 12 in the 7^th, 15 in the 8^th, 25 in the 9^th, 45 in the 10^th, 64 in the 11^th, 58 in the 12^th; K₁ makes 0.5, if the patient is aged one year or less, or K₁ makes 1.0, if the patient is aged more than one year; K₂ makes O_ag 0.5 in 2013; O_ag 0.4 in 2014; O_ag 0.3 in 2015; O_ag 0.4 in 2016; O_ag 0.5 in 2017; O_ag 0.6 in 2018; O_ag 0.6 in 2019; depending on a disease K₃ makes: - apparently healthy - 1.0; - gastrointestinal diseases - 1.2; - non-ulcer dyspepsia - 1.3; - chronic gastroduodenitis - 1.5; - gastric and duodenal ulcer - 1.8; - atrophic gastritis - 1.3; depending on the biomaterial, K₄ makes: - coprofiltrate - 1.0; - saliva - 1.2; - blood serum circulating immune complex - 1.4, and if PI_O falls within the range of 1 to 9%, the probability of H.pylori infection is considered to be doubtful, the PI_O value of 10 to 19% shows the low probability; the PI_O value of 20 to 39% shows the moderate probability, while if the PI_O value is 40 to 100%, the probability is high.

EFFECT: method enables estimating the probability of the Helicobacter pylori infection by the non-invasive method.

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