FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to biochemistry. An aqueous mixture containing phospholipid in an amount of 2 to 50 wt % and a surfactant in an amount of 0.1 to 25 wt % is prepared. The aqueous mixture of phospholipid and surfactant is mixed with serine in an amount of 50 to 80 wt %. The reaction mixture is added with carrot phospholipase D in an amount of 5 to 25 wt %. A reaction of phospholipid and serine is enabled in the presence of water, metal ions and phospholipase D, and at least one surfactant, at temperature 21 - 25° C and at pH ranging from 7 to 10. Phosphatidylserine is recovered from the reaction mixture by filtration.
EFFECT: invention enables producing phosphatidylserine in an amount of 20 - 25 %.
3 ex
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Authors
Dates
2013-05-20—Published
2008-05-15—Filed