NEW COMPOSITIONS STABILISING IMMUNOGENIC COMPOSITIONS AND INHIBITING DEPOSITION THEREOF Russian patent published in 2013 - IPC A61K47/48 A61K47/12 A61K39/09 A61P31/04 

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions refers to medicine, namely biopharmaceutics, and may be used for making vaccines. For this purpose, the composition stabilising a polysaccharide-protein conjugate, contains: (1) buffer saline with said buffer having pKa approximately 3.5 to about 7.5, (2) polysorbate 80 in the final concentration of 0.001% to 0.05 wt/vol % of the composition, and (3) one or more polysaccharide-protein conjugates containing one or more pneumococcal polysaccharides. The group of inventions also relates to a syringe filled with the above composition.

EFFECT: use of this composition can improve the stability of the immunogenic compositions, and inhibit deposition thereof.

28 cl, 8 tbl, 7 dwg, 5 ex