METHOD OF TREATING LOCALLY ADVANCED LARYNGEAL AND LARYNGOPHARYNGEAL CANCERS Russian patent published in 2013 - IPC A61N5/10 A61B17/00 A61M36/00 A61N2/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, oncology, and radiology, and can find application in a combined method of treating laryngeal and laryngopharyngeal cancers. The method involves applying tracheostoma, approaching and excising the tumor, ensuring wound hemostasis and conducting radiotherapy. The tumour excision is followed by making an intraoperative individual tissue-equivalent applicator formed after the bed of resected larynx or laryngopharynx consisting of a self-polymerising material. Conductive ferromagnetic particles and intrastats of the brachytherapeutic apparatus are pre-inserted into the applicator. The applicator is fixed in the tumour bed; the wound is sutured. The local hyperthermia immediately follows through the applicator at 42-43°C for at least 60 minutes. The brachytherapy is conducted immediately thereafter in a single dose of 10 Gy. On the 7-8^th postoperative day, the applicator is removed, and 8-12 days later, the area of the extracted tumor is additionally exposed to the radiation teletherapy (RTT) at a dose of 2 Gy per day, 5 times a week up to a total RTT dose of 24-26 Gy.

EFFECT: method reduces the number of recurrences, provides the radiation dose reduced by 1,5-2 times, reduces the number of complications in healthy tissues.

5 cl, 2 ex