FIELD: medicine.
SUBSTANCE: samples or objects in vivo with or without a drug preparation, as well as a reference objects with the stable optical properties are exposed to optical (laser) radiation either simultaneously, or one by one. The samples may include a patient's biomaterial substrate taken in vivo and/or in vitro. The measured objects in vivo with or without the drug preparation may be represented by areas of inflammation, injury or other pathological tissue, mucosa etc. containing the test drug preparation introduced into the body, as well as intact or unaffected areas of tissue, possibly asymmetrical with the involved ones. When the sample and/or objects in vivo with or without the drug preparation, and/or the reference object are exposed, time dependences of their fluorescence and/or Raman scattering and/or other optical response are measured. Said process (cycle) of measurements is interrupted and repeated with the same or another above-described samples and/or objects in vivo taken from the same or another body and/or in vitro and/or with no biomaterial. The drug preparation is chosen by a degree of decreasing standard fluorescence intensity of the objects with the drug preparation.
EFFECT: higher clinical effectiveness.
10 cl, 1 tbl, 4 dwg
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Authors
Dates
2013-06-20—Published
2010-03-26—Filed