FIELD: medicine.
SUBSTANCE: carbon tetrachloride (CCl4) is introduced orally into male rats at 0.1 ml per 100 g of animal's body weight for 21 days.
EFFECT: method is simple, accessible and safe; it provides a short period of time to simulate subacute hepatic failure adequate to the real clinical conditions that enables the more complete study of the pathophysiological mechanisms of this disease.
2 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR SIMULATION OF SUBACUTE LIVER EXPOSURE TO TOXIC FORMALIN | 2016 |
|
RU2627444C1 |
| METHOD FOR SIMULATING TOXIC HEPATITIS WITH FORMALINE AND ETHANOL IN TOXICOLOGY TEST | 2014 |
|
RU2564758C1 |
| METHOD FOR SIMULATING CHRONIC FORMALIN INTOXICATION IN TOXICOLOGICAL EXPERIMENT | 2014 |
|
RU2564761C1 |
| USING ACIZOL AS HEPATOPROTECTING AGENT | 2004 |
|
RU2260427C1 |
| USE OF POLYDATINE FOR TREATING HEPATIC DISEASES AND POLYDATINE PHARMACEUTICAL COMPOSITION | 2011 |
|
RU2468803C2 |
| METHOD OF TOXIC LIVER DAMAGE REDUCTION | 2007 |
|
RU2342132C2 |
| METHOD OF MODELLING CHRONIC TOXIC HEPATOPATHY | 2010 |
|
RU2440621C1 |
| COMPOSITION AND USING COMPOSITION FOR PREPARING DRUG HAVING HEPATOPROTECTIVE ACTIVITY | 2012 |
|
RU2485970C1 |
| METHOD FOR SIMULATING ACUTE LIVER DISEASE IN PREGNANT WOMEN | 2015 |
|
RU2610536C1 |
| METHOD FOR REDUCING TOXIC DAMAGE OF RATS' LIVER BY A CARBON TETRACHLORATED | 2018 |
|
RU2678313C1 |
