NEW METHOD FOR PREPARING 4,4-(1-METHYL-1,2-ETHANEDIYL)-bis-(2,6,-PIPERAZINEDIONE) Russian patent published in 2013 - IPC C07D241/08 C07C229/16

Abstract RU 2487869 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to a new method for preparing anti-cancer compounds of formula (I) by cycling alkyl esters of tetra acetic acids of formula (II) in the presence of ammonium and formamide, as well as to compounds of formula (ROOCCH₂)₂N-CHCH₃-CH₂-N(CH₂COOR)₂ (II) used in the presented method, wherein R means alkyl.

EFFECT: what is presented is a new effective method for preparing biologically active compounds.

7 cl, 5 ex, 5 tbl

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RU 2 487 869 C2

Authors

Kokh Andreas

Nojfel'Ner Ehrvin

Dates

2013-07-20—Published

2007-11-23—Filed