FIELD: chemistry.
SUBSTANCE: disclosed is (carboxylalkylenephenyl)phenyloxamides of formula 
, where R3 denotes H, F, Cl, Br, CF3, phenyl, COOH, COO-(C1-C6)-alkyl, (C1-C6)-alkyl, (C3-C8)-cycloalkyl, wherein the phenyl can be monosubstituted with: R12; R1, R5 independently denote H, F, Cl, Br, CF3, phenyl, COOH, COO-(C1-C6)-alkyl, (C1-C6)-alkyl; R2, R4 independently denote H, F, Cl, Br, CF3; R7, R8, independently denote H or (C1-C6)-alkyl; X denotes (C2-C3)-alkylene, which can be monosubstituted or multisubstituted with R11; m equals 0; R6 denotes OH, F, Cl, Br, CN, OCH3; OCF3, CH3, CF3, (C1-C6)-alkyl or O-(C1-C6)-alkyl, and the alkyl can be monosubstituted or multisubstituted with OH, F, Cl, Br or CN; R11 denotes (C2-C6)-alkynyl; R12 denotes (C1-C6)-alkyl; and physiologically acceptable salts thereof.
EFFECT: disclosed compounds have activity towards the GPR40 receptor and are suitable for preparing a medicinal agent for reducing blood sugar level, treating diabetes, increasing insulin release, treating diseases of the central nervous system, treating schizophrenia and Alzheimer's disease.
19 cl, 2 tbl, 35 ex
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