DERIVATIVES OF NYSTATIN AND THEIR APPLICATION AS ANTIFUNGAL AGENTS Russian patent published in 2013 - IPC C07H17/08 A61K31/7034 A61P31/10 

Abstract RU 2488590 C2

FIELD: biotechnologies.

SUBSTANCE: compound is proposed with a formula

specified below, or its pharmaceutically acceptable salt, representing a nystatin derivative, having an additional double link, available between C28 and C29, and additionally modified relative to nystatin according to position C16. These compounds are used as antifungal agents. Also in the invention a pharmaceutical composition is announced, and its manufacturing to treat fungal infections, as well as the method to treat a fungal infection of an animal, including introduction of an efficient compound dose to the specified animal.

EFFECT: improved efficiency of compound application.

10 cl, 29 ex, 17 dwg, 15 tbl

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Authors

Zotchev Sergej Borisovich

Borgos Sven Ehven Finn

Brautaset Trjugve

Ehllingsen Tron Ehrling

Olsuf'Eva Evgenija Nikolaevna

Preobrazhenskaja Marija Nikolaevna

Sletta Khavard

Dates

2013-07-27Published

2008-06-30Filed