FIELD: chemistry.
SUBSTANCE: present invention relates to salts of acetate, L-glutamate, citrate or fumarate of amphotericin B N-(2-aminoethyl)amide of formula I
,
which can be used in medicine. Pharmaceutical compositions are effective against diseases caused by C. albicans, C. parapsilosis, C. krusei, C. tropicalis, C. glabrata, M. canis, T. Rubrum, Aspergillus.
EFFECT: novel antifungal compounds with reduced toxicity and improved stability, pharmaceutical compositions based thereon for treating fungal infections.
10 cl, 5 dwg, 2 tbl, 8 ex
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