FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions refers to medicine, namely to STAT3/5 activation inhibitor representing an aromatic compound, represented by general formula I. Also, there are provided method of preventing or treating a symptom or disease associated with STAT3 activation by administering an effective amount of the aromatic compound or a salt thereof to a patient. And the method of preventing or treating the symptom or disease associated with STAT5 activation by administering the effective amount of the aromatic compound or the salt thereof.
EFFECT: group of invention provides preventing and treating diabetes, diseases of the nervous system, diseases associated with cancer and psoriasis, autoimmune diseases, allergy and hyperprolactinemia.
9 cl, 4 tbl, 4 ex
| Title | Year | Author | Number |
|---|---|---|---|
| AROMATIC COMPOUND | 2005 |
|
RU2416608C2 |
| DRUG PREPARATION | 2006 |
|
RU2444362C2 |
| COMBINATIONS CONTAININS Bcr-Abl/c-Kit/PDGF-RTK INHIBITORS FOR TREATING CANCER | 2007 |
|
RU2452492C2 |
| SUBSTITUTED CONDENSED HETEROCYCLIC COMPOUND, METHOD OF PHARMACOLOGICAL EFFECT, METHOD OF INHIBITION OF 5-LIPOXYGENASE ACTIVITY, INHIBITION OF LIPID PEROXIDES PRODUCTION OR BLOOD SUGAR LEVEL DECREASE | 1998 |
|
RU2196141C2 |
| NOVEL AMINOPYRIDINE DERIVATIVES HAVING AURORA A SELECTIVE INHIBITORY ACTION | 2007 |
|
RU2437880C2 |
| COMPOUND WITH SUCCESSIVE ARICYCLIC STRUCTURE, POSSESSING ACTIVITY OF INHIBITING ACYCLOENZYME A DIACYLGLYCEROLACYLTRANSFERASE (DGAT1) | 2011 |
|
RU2538964C1 |
| 4-SUBSTITUTED PHENOXYPHENYLACETIC ACID DERIVATIVES | 2007 |
|
RU2463292C2 |
| DIHYDROPYRAZOLOPYRIMIDINONE DERIVATIVES | 2007 |
|
RU2437885C2 |
| DERIVATIVES OF PHENYLALKYLCARBOXYLIC ACID AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF | 1997 |
|
RU2169141C2 |
| SULFONAMIDE DERIVATIVE AND MEDICINAL USE THEREOF | 2014 |
|
RU2667520C9 |
