AROMATIC COMPOUND Russian patent published in 2011 - IPC C07D295/192 C07D211/46 C07D211/58 C07D211/62 C07D211/70 C07D213/75 C07D239/42 C07D241/20 C07D295/18 C07D317/58 C07D401/12 C07D401/14 C07D405/12 C07D405/14 C07D409/12 C07D409/14 C07D413/12 C07D413/14 C07D417/12 C07D417/14 A61K31/435 A61P11/00 

Abstract RU 2416608 C2

FIELD: chemistry.

SUBSTANCE: invention describes a novel compound of general formula (1), where radicals R1, R2, X1, Y and A are as described in claim 1 of the invention. The invention also describes a method of obtaining compounds of formula (1), as well as a pharmaceutical composition based on said compounds, for treating fibrosis.

EFFECT: novel compounds with excellent collagen formation suppression, cause fewer side-effects and which are safer are obtained.

62 cl, 2717 ex, 432 tbl

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RU 2 416 608 C2

Authors

Fukusima Tae

Matsumura Sudzi

Takemura Noriaki

Satou Khideaki

Ito Nobuaki

Sitsuta Takuja

Tsutsui Khironori

Tanaka Mitinori

Kan Keizo

Nagao Khitosi

Vatanabe Kendzi

Tai Kuninori

Nakagava Takasi

Takasu Khideki

Sakamoto Makoto

Mijadzima Keisuke

Jamada Satosi

Kodzima Jutaka

Jasumura Koiti

Okhi Naoto

Okuno Mitsukhiro

Sugijama Kazukhisa

Kijono Kunikhiko

Suzuki Takasi

Akamatsu Seidzi

Kodama Takesi

Janagikhara Jasuo

Sumida Takumi

Dates

2011-04-20Published

2005-08-03Filed