FIELD: chemistry.
SUBSTANCE: invention describes a novel compound of general formula (1), where radicals R1, R2, X1, Y and A are as described in claim 1 of the invention. The invention also describes a method of obtaining compounds of formula (1), as well as a pharmaceutical composition based on said compounds, for treating fibrosis.
EFFECT: novel compounds with excellent collagen formation suppression, cause fewer side-effects and which are safer are obtained.
62 cl, 2717 ex, 432 tbl
Title | Year | Author | Number |
---|---|---|---|
DRUG PREPARATION | 2006 |
|
RU2444362C2 |
STAT3/5 ACTIVATION INHIBITOR | 2007 |
|
RU2489148C2 |
SULFONAMIDE DERIVATIVE AND MEDICINAL USE THEREOF | 2014 |
|
RU2667520C9 |
CARBOSTYRIL COMPOUND | 2005 |
|
RU2430920C2 |
METHOD OF OBTAINING 4-NITROIMIDAZOLE COMPOUND | 2005 |
|
RU2345071C2 |
WAY OF PRODUCTION OF OPTICALLY ACTIVE AMINOPHOSPHINYLBUTANOIC ACIDS | 2007 |
|
RU2442787C2 |
DIHYDROPYRAZOLOPYRIMIDINONE DERIVATIVES | 2007 |
|
RU2437885C2 |
TRICYCLE HETEROCYCLIC COMPOUNDS, METHOD OF THEIR SYNTHESIS AND PHARMACEUTICAL COMPOSITION | 1992 |
|
RU2072997C1 |
NOVEL PYRIDONE DERIVATIVES, HAVING MCH ANTAGONIST ACTIVITY, AND MEDICINAL AGENT CONTAINING SAID COMPOUNDS | 2007 |
|
RU2453543C2 |
DERIVATIVES OF 3(2H)-PYRIDAZINONE AND THEIR PHARMACEUTICALLY ACCEPTABLE SALTS AND PHARMACEUTICAL COMPOSITION ON THEIR BASE | 1991 |
|
RU2054004C1 |
Authors
Dates
2011-04-20—Published
2005-08-03—Filed