FIELD: biotechnologies.
SUBSTANCE: invention relates to new compounds of the formula I:
or its pharmaceutically acceptable salts, where values R1, R2, R3, R3', R4, R4', X2, X1, X3, X4, X5, R6, R7, R5', R6', R7', R14', R8, R9, R10, R11a, b, c are specified in the clause 1 of the formula.
EFFECT: compounds demonstrate antitumoral activity and may be used to produce a pharmaceutical composition for tumor treatment in a mammal.
14 cl, 18 dwg, 1 tbl, 52 ex
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