METHOD OF TREATING CANCER Russian patent published in 2011 - IPC A61K48/00 A61K31/675 A61P35/00 

Abstract RU 2429019 C2

FIELD: medicine.

SUBSTANCE: method involves introduction in a patient's body cyclophosphan, a preparation of a cytostatic group which is introduced in dose 20 to 100 mg/kg of body weight and a preparation of fragmented allogenic two-chained genomic DNA with fragments having a biologically active value and composing a full genome of physiologically and genetically healthy donor (hereinafter - exogenic DNA). The exogenic DNA preparation is introduced 48 hours after each introduction of the cytostatic preparation and for the following 30 days for the scheme when the patient has taken a full course dose 6-14 g, or for the following 3-5 days after a single injection and one day before a following injection with continuing with such intermittent to a complete setting of a therapeutic or supporting dose of the cytostatic preparation.

EFFECT: use of the invention allows higher clinical effectiveness in tumours ensured by differentiated inhibition of cytotoxic and regulatory lymphocyte viability under the effect of cyclophosphan and exogenic DNA.

3 tbl, 9 dwg

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RU 2 429 019 C2

Authors

Aljamkina Ekaterina Anatol'Evna

Dolgova Evgenija Vladimirovna

Likhacheva Anastasija Sergeevna

Rogachev Vladimir Alekseevich

Sebeleva Tamara Egorovna

Nikolin Valerij Petrovich

Popova Nelli Aleksandrovna

Orishchenko Konstantin Evgen'Evich

Strunkin Dmitrij Nikolaevich

Chernykh Elena Rehmovna

Zagrebel'Nyj Stanislav Nikolaevich

Bogachev Sergej Stanislavovich

Shurdov Mikhail Arkad'Evich

Dates

2011-09-20Published

2009-08-03Filed