FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to pharmaceutics and medicine, and concerns a pharmaceutical composition for preventing and treating diseases mediated by high expression or high activity of liver X receptor (LXRa), high expression or high activity of a sterol regulatory element-binding protein-1c (SREBP-1).
EFFECT: preventing and treating renin hypertension, hyperaldosteronism, adrenoleukodystrophy, glomerular sclerosis, proteinuria, nephropathy, hepatic steatosis, hypertriglyceridemia or hyperreninemia, possessing high activity.
6 cl, 11 dwg, 9 ex
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