TREATMENT OF HEPATIC ADIPOSITIS WITH APPLICATION OF GLUCOCORTICOID AND MINERALOCORTICOID RECEPTOR ANTAGONISTS Russian patent published in 2020 - IPC A61K31/513 A61P1/16 

Abstract RU 2718921 C2

FIELD: medicine.

SUBSTANCE: invention refers to medicine and concerns treating fatty liver disease. For this purpose, a subject in need thereof is administered a therapeutically effective amount of a glucocorticoid receptor and mineralocorticoid receptor antagonist compound such as (E)-6-(4-phenylcyclohexyl)-5-(3-trifluoromethylbenzyl)-1H-pyrimidine-2,4-dione or 6-((1r,4r)-4-phenyl-cyclohexyl)-5-(3-(trifluoromethyl)benzyl)pyrimidine-2,4(1H, 3H)-dione.

EFFECT: invention provides treating fatty liver disease.

12 cl, 4 dwg, 5 ex

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Authors

Belanoff Dzhozef K.

Khant Khejzel

Mejer Onno K.

Van Den Khevel Khose

Dates

2020-04-15Published

2015-10-14Filed