METHOD OF TREATING HEPATIC FIBROSES Russian patent published in 2021 - IPC A61K31/437 A61K31/4427 A61K31/18 A61P1/16 C07D471/02 

Abstract RU 2740902 C2

FIELD: medicine.

SUBSTANCE: invention relates to a method of treating hepatic fibrosis in a patient, comprising administering to a patient in need thereof an effective amount of a compound of formula I or a pharmaceutically acceptable salt thereof, where R1 is halogen, R2 is C1-6 haloalkyl, R3 is C1-6 alkyl, R4 is hydrogen, and each of A1, A2 is -CH-, and A3 is -N-.

EFFECT: technical result is a novel method of treating hepatic fibrosis, in which hepatic fibrosis is associated with non-alcoholic steatohepatitis (NASH).

6 cl, 6 dwg, 1 tbl, 5 ex

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RU 2 740 902 C2

Authors

Miao Zhenhua

Charo Israel

Dates

2021-01-21Published

2017-06-02Filed