NOVEL COMPOUNDS WITH SPIROCHIRAL CARBON BASE, METHODS OF THEIR OBTAINING AND PHARMACEUTICAL COMPOSITIONS WHICH CONTAIN SUCH COMPOUNDS Russian patent published in 2013 - IPC C07D493/10 C07D493/02 C07D493/04 A61K31/35 A61P19/10 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to novel compound with spirochiral carbon base, or its pharmaceutically acceptable salt of general formula 1 , where W represents CO or CHO(C=O)CH₃; X represents N₃ or OR₂; R₂ represents hydrogen, linear or branched alkyl C1~C8 or Y represents O; Z represents simple bond or O; R₃ represents linear or branched alkyl C1~C8 or alkenyl C2~C8, and M and N represent, each independently, hydrogen, OH or are absent; carbon atom, bound with M or N forms simple bond or double bond with other carbon atoms, and number of double bonds constitutes one or less for each of carbon atoms. Invention relates to method of obtaining and pharmaceutical compositions.

EFFECT: compound with spirochiral carbon base possesses excellent activity of osteoblast differentiation, activity of inhibiting mast cells and activity of inhibiting synthesis of fatty acids in liver that is why compound will play leading role in treatment of steoporosis, fatty liver dystrophy and obesity.

13 cl, 6 ex, 5 tbl, 17 dwg