FIELD: biotechnology.
SUBSTANCE: group of inventions relates to biotechnology, specifically to a composition for inducing stem cell differentiation into adipocytes. Composition for inducing stem cell differentiation into adipocytes for regenerating fatty tissues comprises as an ingredient, exosomes, obtained from adipose tissue-derived stem cells and differentiated into adipocytes, where the exosomes are characterized by that they contain macrophage colony-stimulating factor (MCSF), tumour necrosis factor-α (TNF-α), leptin, insulin, angiopoietin-1 (ANGPT1) and adiponectin with molecular weight 30 kDa (Acrp30). Group of inventions also relates to injection form of preparation containing said composition.
EFFECT: using the given group of inventions enables using the given composition as agents inducing stem cell differentiation, injection forms of tissue regeneration products by exosomes expression of bioactive factors effecting differentiation into adipocytes.
6 cl, 20 dwg, 5 tbl, 2 ex
| Title |
Year |
Author |
Number |
| COMPOSITION INCLUDING EXOSOME OBTAINED FROM STEM CELLS FOR INDUCTION OF ADIPOGENIC DIFFERENTIATION, REGENERATION OF FAT TISSUE, SKIN WHITENING OR CORRECTION OF WRINKLES |
2021 |
- Cho Yong Woo
- Choi Ji Suk
- Yang Seong Hyun
- Lee Kyoung-Soo
- Kim Eun Ji
- Yoon Hwa In
- Kim Jun Sung
|
RU2759508C1 |
| COMPOSITION INCLUDING EXOSOME PRODUCED FROM STEM CELLS FOR INDUCING ADIPOGENOUS DIFFERENTIATION, REGENERATION OF FATTY TISSUE, SKIN WHITENING OR WRINKLE CORRECTION |
2015 |
- Cho Yong Woo
- Choi Ji Suk
- Yang Seong Hyun
- Lee Kyoung-Soo
- Kim Eun Ji
- Yoon Hwa In
- Kim Jun Sung
|
RU2750695C2 |
| METHOD OF OBTAINING EXOSOMES ORIGINING FROM MESENCHYMAL STEM CELLS AND A CULTURAL SOLUTION PRODUCED FROM THEM |
2020 |
- Kim, Jae Young
- Chwae, Yong Joon
|
RU2799432C1 |
| METHOD FOR PRODUCING SECRETOME OF MESENCHYMAL STROMAL CELLS CONTAINING EXOSOME FRACTION |
2023 |
- Didenko Nikolai Nikolaevich
- Bobryshev Dmitrii Viktorovich
- Dolgalev Aleksandr Aleksandrovich
- Boiko Evgenii Mikhailovich
|
RU2827355C1 |
| EXOSOME ISOLATED FROM SEPTAL CARTILAGE USED TO OBTAIN CARTILAGE TISSUE |
2019 |
- Sahin, Fikrettin
- Tasli, Pakize Neslihan
- Avsar Apdik, Ezgi
- Apdik, Huseyin
- Safak, Ayse Sezim
|
RU2833888C2 |
| METHOD OF PRODUCING AND CONCENTRATING microRNA-CONTAINING EXOSOMES OF MULTIPOTENT MESENCHYMAL STROMAL CELLS FOR USE IN COSMETIC AND MEDICINAL AGENTS FOR STIMULATING REGENERATIVE PROCESSES AND SLOWING DOWN AGING PROCESSES |
2018 |
- Volchkov Stanislav Evgenevich
- Tyumina Olga Vladimirovna
|
RU2710368C2 |
| STEM CELLS AND MATRICES OBTAINED FROM ADIPOSE TISSUE |
2000 |
- Katts Adam Dzh.
- L'Ul' Ramon
- Fatrell Dzh. Vill'Jam
- Khedrik Mark Kh.
- Benkhehjm Prosper
- Lorents Germann Piter
- Zu Min
|
RU2306335C2 |
| METHOD OF TREATING COSMETIC SKIN DEFECTS |
2024 |
- Samokhvalov Igor Mikhailovich
- Trofimov Petr Sergeevich
|
RU2831472C1 |
| METHOD FOR ISOLATION OF PLURIPOTENT STEM CELLS FROM UMBILICAL BLOOD EXPRESSING ZNF281 |
2010 |
- Kang Kiung Sun
- Rokh Kioung Khvan
|
RU2511417C2 |
| BIOMATERIAL BASED ON CELL-FREE MATRIX PRODUCED BY HUMAN MESENCHYMAL STROMAL CELLS, METHOD FOR PREPARING THEREOF AND METHOD OF USING THEREOF TO STIMULATE REGENERATIVE PROCESSES |
2018 |
- Tkachuk Vsevolod Arsenevich
- Akopyan Zhanna Alekseevna
- Efimenko Anastasiya Yurevna
- Grigoreva Olga Aleksandrovna
- Makarevich Pavel Igorevich
- Nimiritskij Petr Petrovich
- Novoseletskaya Ekaterina Sergeevna
|
RU2718907C1 |
