5-(2-{[6-(2,2-DIFLURO-2-PHENYLETHOXY)HEXYL]AMINO}-1-HYDROXYETHYL)-8-HYDROXYQUINOLIN-2(1H)-ONE HEMINAPADISYLATE AS β2 ADRENERGIC RECEPTOR AGONIST Russian patent published in 2013 - IPC C07D215/26 A61K31/4704 A61P11/00 

Abstract RU 2495029 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one heminapadisylate of formula (I) wherein n is equal to 2, and to pharmaceutically acceptable solvates thereof. Also, the invention refers to a pharmaceutical composition of the salt of formula (I), to a method of treating the above pathological conditions and to using the salt of formula (I) and to the pharmaceutical composition thereof.

EFFECT: what is prepared is the new salt of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one effective in treating the pathological pulmonary conditions, particularly asthma or chronic obstructive pulmonary disease.

11 cl, 3 dwg, 6 ex

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RU 2 495 029 C2

Authors

Puig-Duran Karlos

Mojes-Vall'S Ehnrike

Dates

2013-10-10Published

2008-02-08Filed