METHOD OF PREDICTING DURATION OF ARTIFICIAL LUNG VENTILATION IN PATIENTS WITH SYNDROME OF ACUTE LUNG INJURY Russian patent published in 2013 - IPC A61B5/02 A61B5/08 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to intensive therapy (IT) and can be used in treatment of patients, who are on long artificial lung ventilation (ALV) in case of syndrome of acute lung injury. For this purpose parameters of respiration and gas exchange biomechanics are registered in patients of over 53 years old with initial severity in accordance with ARACHE II not lower than 13 points, TISS for the first day lower than 34 points. Ventilation is performed for 60 minutes in mode of high-frequency ALV (HF ALV) with initial specified parameters for normal ventilation with constant monitoring of oxymetry, capnometry, elecrocrdiography, as well as parameters of peripheral hemodynamics and average pressure in respiratory tract. After 60 minutes of HF ALV carrying out, the following indices are registered: partial oxygen pressure in arterial blood p_aO₂, partial oxygen pressure in venous blood p_vO₂, FiO₂/p_aO₂ - coefficient of oxygenation, static compliance Cst=VT/(Pplateau -PEEP), VT - volume of respiration, Pplateau - plateau pressure, PEEP - positive expiration end pressure, auto PEEP - internal PEEP, partial pressure of carbon dioxide in arterial blood -P_aCO₂, saturation of hemoglobin with oxygen in arterial blood, SaO₂, saturation of hemoglobin with oxygen in venous blood SvO₂, hydrogen index pHart - measure of hydrogen ion activity in solution, oxygenation index and deficiency of bases. Increase of arterial oxygenation by 10 and more Hg mm in comparison with the initial one is considered to be predictor of reduction of ALV and IT terms.

EFFECT: method ensures the most exact prediction of ALV duration in said category of patients due to identification of HF ALV test as ALV duration predictor.

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