TARGETING OF ANTIGEN-PRESENTING CELLS OF IMMUNONANOTHERAPY DRUGS Russian patent published in 2013 - IPC A61K39/00 

Abstract RU 2497542 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions refers to medicine and concerns a composition for the immune system induction, containing synthetic nanoparticles with at least one surface having the immune properties and formed by a number of molecules providing high binding avidity and low binding affinity with antigen-presenting cells (APC), and a pharmaceutically acceptable excipient; a method for the immune system induction involving the administration of the above composition into an individual.

EFFECT: group of inventions provides the targeted delivery to the antigen-presenting cells once administered into the individual.

30 cl, 18 ex, 41 dwg

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Authors

Shi Tszin'Tszjun'

Aleksis Frank

Iannakone Matteo

Mouzman Ehlliott Ehshli

Basto Pamela

Langer Robert

Farokkhzad Omid K.

Von Andrian Ul'Rikh

Tonti Elena

Dates

2013-11-10Published

2009-10-09Filed