METHOD OF ESTIMATING STATE OF PULMONARY SURFACTANT Russian patent published in 2013 - IPC A61B5/08 G01N13/02 

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to pulmonology, and can be applied for estimation of state of pulmonary surfactant. For this purpose components of pulmonary surfactant are collected by barbotation of exhaled air through a layer of isotonic physiological solution, placed into glass burette and tray of Langmuir barrier system. After that, static surface tension of obtained exhaled air barbotate is measured in burette by anchor ring method. After that, in Langmuir barrier system tray surface pressure Δσ is measured by Wilhelmy method with reduction of area between barriers by 90%. If static surface tension decreases to 37±8 dyn/cm after 5 minutes of barbotation and/or surface pressure Δσ increases from 4.5±1.0 dyn/cm after first inhalation to 17.0±3.0 dyn/cm after fifth inhalation, normal antiatelectatic function of pulmonary surfactant is diagnosed.

EFFECT: method ensures increase of efficiency of pulmonary surfactant aerosol collection from exhaled air with reduction of time for test performance.

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