LAYERS FOR MECHANICAL PROTECTION OF SOLID DOSAGE FORMS Russian patent published in 2013 - IPC A61K9/16 A61K9/26 A61K9/32 A61K9/42 A61K31/4439 A61P1/04 

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to a layer for mechanical protection of dosage forms, containing two or more plasticizing agents, wherein the first plasticizing agent represents first polyethylene glycol of average molecular weight between 3000 and 6000, and the second plasticising agent represents second polyethylene glycol of average molecular weight between 5000 to 7000. The above layer for mechanical protection is found on an enteric coated granule. The declared invention also refers to the pharmaceutically acceptable enteric solid dosage forms comprising the layer for mechanical protection, and to methods for preparing and using the above layer.

EFFECT: declared invention prevents the mechanical damage of the solid dosage forms, especially compression, as well as provides their resistance to gastric acid.

21 cl, 1 dwg, 6 tbl, 10 ex