METHOD OF TREATING SEPSIS ACCOMPANYING ABDOMINAL AND RETROPERITONEAL DISEASES Russian patent published in 2013 - IPC A61M1/34 A61K31/538 A61K31/718 A61P31/04 A61P3/12 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely surgery and intensive care, and may be used in treating the patients with developed sepsis with underlying abdominal and retroperitoneal diseases. For this purpose, the management starts with a session of endotoxin absorption. That is followed by the intravenous administration of a bactericidal antibiotic, e.g. such as β-lactam or fluoroquinolone in the amount of 1.1-1.5 daily dose; then 30-60 minutes later, endotoxin sorption is combined with de-hydration hemofiltration in a dose of 45 ml/kg/h for 6-8 hours. The whole procedure is accompanied by the infusion therapy using active solutions specified in a group of low- and high-molecular hydroxyethyl starch and dextran in the amount of 5-10 ml/kg/h. Before the beginning of endotoxin sorption, as well as one day after the termination of hemofiltration and sorption, the blood endotoxin concentration is controlled. If the recorded endotoxin concentration is decreased at least by 60%, another procedure is performed.

EFFECT: method provides higher survival rate in the patients suffering the above pathology, as well as reduces a risk of septic shock ensured by the pathogenically caused regimen of the combination of various human body effects providing a degree of systemic endotoxemia to be decreased.

2 cl, 2 ex