FIELD: medicine.
SUBSTANCE: method involves a selective sorption of endotoxin through a vascular access, and an infusion therapy with administering an antibiotic. The absorption is preceded by an infusion of 10% albumin into a portal vein in an amount of 100 ml. The infusion is followed by the selective sorption of gram-negative flora endotoxins through the portal vein 30-45 minutes after the albumin infusion is completed. The gram-negative flora active antibiotic is infused into the portal vein during the whole period of the sorption; after the procedure is completed, a hepatoprotector is administered into the portal vein.
EFFECT: method enables achieving higher survival rate in this category of patients, providing earlier and more complete reduction of activity of the systemic inflammatory response, and causes the faster stabilisation of haemodynamics and reduction of multiple organ failure symptoms.
2 ex
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Authors
Dates
2015-12-27—Published
2014-11-12—Filed