METHOD OF PREDICTING COURSE OF REPARATIVE OSTEOGENESIS IN SURGICAL TREATMENT OF FALSE JOINTS OF LONG TUBULAR BONES Russian patent published in 2013 - IPC A61B8/06 

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine, namely to traumatology and orthopedics. Before surgical treatment of false joints of tubular bones non-invasive laser Doppler flowmetry is carried out. Examination is performed with patient in sitting position after 30-minute rest and with placement of sensor on intact patient's skin in projection of false joint of long tubular bone for 300-360 seconds with wavelength of red laser radiation 0.63 mcm and volume of probing 0.8-0.9 mm³ with application of spectral wavelet-analysis of blood flow oscillation. Microhemocirculation index (MI) of soft tissues in projection of false joint of patient's long tubular bone is measured and assessed. Oscillatory component of total perfusion is measured and assessed by standard deviation of blood flow σ. Variation coefficient (K_v) is calculated by formula. macroscopic behaviour of blood flow system in examined zone of microcirculatory nets is measured and assessed by indices of non-linear dynamics, namely fractal Hausedorff dimension (D0) and correlation dimension (D2) of phase portrait of microflow behaviour. If measured characteristic of soft tissue microhemoregulation index in projection of false joint constitutes 3.7-4.4 perfusion units (p.u.), measured value of nutritive blood flow constitutes 1.88-1.92 p.u., K_v value constitutes 20.3-28.3; D0 value constitutes 1.35-1.41 and D2 of 1.32-1.37, adequate reparative osteogenesis, which does not require additional application of biological stimulators in its implementation, is predicted. In case, if value of measured index of microhemocirculation of soft tissues in projection of false joint constitutes 1.86-2.86 p.u., measured value of nutritive blood flow constitutes 1.17-1.23 p.u., K_v value constitutes 43.6-54.0, D0 value constitutes 1.29 -1.34 and D2 value of phase micro-blood flow circulation constitutes 1.29-1.30, deficit of reparative osteogenesis with risk of non-union or delayed body fusion is predicted.

EFFECT: course of reparative osteogenesis is assessed at preoperative level due to measurement of regional metabolism and bone regeneration, with selection of individual tactics of surgery with application of biological osteogenesis stimulators and with possible application of free vascularised autotransplants.

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