USING PENTAAMINOFULLERENES AS ANTIMICROBIAL AGENTS AND ANTIMICROBIAL COMPOSITION BASED THEREON Russian patent published in 2013 - IPC C07C211/38 C07D241/04 A61K31/132 A61K31/4965 A61P31/00 B82B1/00 

FIELD: chemistry.

SUBSTANCE: in formula 1 , X denotes a negative charge which is localised on a fullerene skeleton, a chlorine atom bonded to a carbon skeleton or a hydrogen atom; the NR¹R² moiety denotes an amine residue, where R¹ and R² are hydrogen atoms or linear or branched alkyl radicals (C_mH_2m+1; n=1-20) that are substituted with protonated (NH₃ ⁺) or unprotonated (NH₂) amine groups, or a piperazine residue of general formula 1c-1 , where R, R'₁, R'₂, R'₃ and R'₄ are hydrogen atoms or linear or branched alkyl (C_mH_2m+1; n=1-20) radicals, as well as residues of aliphatic alcohols -(CH₂)_nOH, ethers -(CH₂)_nOR'₅, thiols -(CH₂)_nSH, acids -(CH₂)_nCOOH, esters thereof -(CH₂)_nCOOR'₅ or amides -(CH₂)_nCONR'₅R'₆, for which n=0-20, R'₅ and R'₆ are hydrogen atoms or linear alkyl (C_mH_2m+1; n=1-20) radicals.

EFFECT: stronger or prolonged antibacterial action.

2 cl, 2 dwg, 2 tbl, 3 ex