METHOD OF PREDICTING UNFAVOURABLE ANNUAL OUTCOME IN PATIENTS WITH ACUTE CORONARY SYNDROME WITH ELEVATION OF ST SEGMENT AFTER PERCUTANEOUS CORONARY INTERVENTION Russian patent published in 2013 - IPC A61B5/00 G01N33/48 

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine, namely to cardiology. To predict unfavorable annual outcome in patients with acute coronary syndrome with elevation of ST segment, subjected to percutaneous coronary intervention, results of clinical and laboratory examination methods are analysed. On the first day of disease presence of II-IV class of heart failure by Killip classification, impairment of rhythm and conductivity of heart, patient's smoking in anamnesis, as well as determination of TNF-α in patient's blood plasma are taken into account. On the tenth day IL1α and sP-selectin are determined in blood plasma. Value of TNF-α≥4.5 pg/ml is assessed in 8 points; level of IL1α≥0.69 pg/ml is assessed in 3 points; sP-selectin≥152.8 ng/ml - in 2 points; class of heart failure by Killip II-IV - in 3 points; presence of impairment of rhythm and conductivity - in 1 point; smoking in anamnesis - in 1 point. Patients with the sum of points from 0 to 4 are related to group I of low risk of development of unfavourable coronary events, group II, of intermediate risk, is determined by the sum 5-10 points; and patients with the sum of points 11-18 constitute group III, of high risk.

EFFECT: method makes it possible to predict unfavourable annual outcome in patients with acute coronary syndrome with elevation of ST segment after percutaneous coronary intervention.

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