FIELD: medicine, pharmaceutics.
SUBSTANCE: presented group of inventions refers to immunology and medicine. There are presented compositions containing a digoxin antibody for weakening the action of tumour necrosis factor on a cell adhesion molecule and for weakening the TNF induction of ICAM, VCAM and E-selectin expression in an endothelial cell. What is presented is a method for weakening the cytokine-induced surface expression of the cell adhesion molecule involving the stage of cell contact to a digoxin antibody composition.
EFFECT: group of inventions provides the effective weakening of the cytokine-induced TNF-α surface expression of the ICAM, VCAM and E-selectin molecules due to contacting the cell in need thereof with the digoxin antibody composition.
5 cl, 12 dwg, 6 tbl, 4 ex
