METHOD OF 1-DICYANOGEN-2-(2-CHLORPHENYL)ETHYLENE UTILISATION Russian patent published in 2014 - IPC A62D3/33 A62D101/02 A62D101/22 

Abstract RU 2503474 C2

FIELD: chemistry.

SUBSTANCE: invention relates to utilisation of irritating toxic substances (irritants) to nontoxic products, able to find practical application in fine organic synthesis, chemistry of physiologically active substances and medical products. Method of 1-dicyanogen-2-(2-chlorphenyl)ethylene utilisation consists in the following: 1-dicyanogen-2-(2-chlorphenyl)ethylene interacts in solvent with 2-chlorine-1-phenylethanol in presence of ammonium acetate with molar ratio equal to 1:1:2, in acetic acid medium at temperature 60°C, formed crude product 2-phenyl-3-chlorine-4(2-chlorphenyl)-5-cyanogen-6-amine-1-pyridine is filtered, washed with cold ethyl alcohol to pH-6…7 and recrystallised from ethyl alcohol with obtaining pure product.

EFFECT: invention makes it possible to apply in utilisation available and cheap reagents, carry out reaction under soft conditions with simultaneous application in reaction of two substances, which require utilisation.

1 ex

Similar patents RU2503474C2

Title Year Author Number
METHOD OF 2-CHLORO-1-PHENYLETHANONE-1 UTILISATION 2007
  • Migachev Jurij Sergeevich
  • Migachev Aleksej Sergeevich
  • Sorokin Pavel Aleksandrovich
  • Sin'Kelev Aleksandr Petrovich
  • Solovykh Sergej Nikolaevich
  • Kuznetsova Svetlana Viktorovna
  • L'Vov Aleksej Nikolaevich
RU2359724C1
METHOD OF UTILISING TOXIC CHLORINE-CONTAINING SUBSTANCE 2-(2-CHLOROBENZYLIDENE)MALONODINITRILE(CS) 2012
  • Sheverdov Vladimir Petrovich
  • Nasakin Oleg Evgen'Evich
RU2506978C1
METHOD OF RECYCLING 2-CHLORO-1-PHENYLETHANOL-1 2007
  • Smirnov Evgenij Aleksandrovich
  • Migachev Jurij Sergeevich
  • Migachev Aleksej Sergeevich
  • Sin'Kelev Aleksandr Petrovich
  • Solovykh Sergej Nikolaevich
  • Kuznetsova Svetlana Viktorovna
  • L'Vov Aleksej Nikolaevich
RU2386612C2
METHOD OF REUSING 2-CHLORO-1-PHENYLETHAN-1-ONE 2000
  • Gormaj V.V.
  • Chernov S.A.
  • Alimov N.I.
  • Basharin Ju.V.
  • Savostin V.S.
RU2178718C2
DERIVATIVES OF PYRIDINE, THEIR ENANTIOMERS, CIS- OR TRANS-ISOMERS AND THEIR SALTS AND PHARMACEUTICAL COMPOSITION 1992
  • Rajner Zojka
  • Tomas Mjuller
  • Iogannes Vejzenberger
RU2119915C1
0
  • Kurt Ejkhenberger
  • Paul Shmidt
  • Ernst Shvejtser
SU504492A3
DERIVATIVES OF AMINO-7-(CHRR)-3H,5H-PYRROLO-[3,2-D]-PYRIMIDINE-4-ONE, METHODS OF THEIR SYNTHESIS AND A METHOD OF SELECTIVE INHIBITION OF MAMMALIAN T-LYMPHOCYTES PROLIFERATION AND NO EFFECTING ON CHRR-LYMPHOCYTES 1992
  • Dzhon A.Sekrist Iii[Us]
  • Mark Dehvid Ehrion[Us]
  • Dzhon A.Montgomeri[Us]
  • Stiven Eh.Ilik[Us]
  • Vejn S.Gajda[Us]
  • Shri Nivas[Us]
RU2097384C1
DERIVATIVES OF 4-ARYL-6-AMINONICOTINIC ACID AND THEIR SALTS 1995
  • Klaus Urbans
  • Zigfrid Gol'Dmann
  • Khans-Georg Khejne
  • Bodo Junge
  • Rudol'F Shokhe-Loop
  • Khenning Zommermejer
  • Tomas Glazer
  • Rejlinde Vittka
  • Zhan-Mari-Viktor De Vri
RU2154635C2
INDOLE-2-CARBOXAMIDES AS INHIBITORS OF FACTOR Xa AND/OR VIIa, MEDICINAL AGENT BASED ON THEREOF AND METHOD FOR THEIR PREPARING 2002
  • Nazare Mark
  • Ehssrikh Melani
  • Uill Dehvid Uill'Jam
  • Matter Khans
  • Ritter Kurt
  • Vener Fol'Kmar
RU2299881C2
SUBSTITUTED 2-THIO-3,5-DICYANO-4-ARYL-6-AMINOPYRIDINES AND THEIR USING 2000
  • Rozentreter Ul'Rikh
  • Khenning Rol'F
  • Bauzer Markus
  • Krehmer Tomas
  • Faupel' Andrea
  • Khjubsh Val'Ter
  • Dembovski Klaus
  • Zal'Kher-Shraufshtetter Ol'Ga
  • Shtash Jokhannes-Peter
  • Kran Tomas
  • Pertsborn Ehlizabet
RU2267482C2

RU 2 503 474 C2

Authors

Migachev Jurij Sergeevich

Migachev Aleksej Sergeevich

Migachev Viktor Alekseevich

Dates

2014-01-10Published

2012-04-11Filed