FIELD: biotechnologies.
SUBSTANCE: invention presents a method for obtaining pyrroloquinoline quinone (PQQ) using the bacterium belonging to Methylobacterium or Hyphomicrobium type. The above bacteria are modified so that expression of cluster of pqq genes is intensified in the above bacterium. In addition, the bacterium can be also modified so that expression of pqqA-like gene(s) is intensified.
EFFECT: invention allows obtaining pyrroloquinoline quinone with high efficiency degree.
20 cl, 10 dwg, 5 tbl, 5 ex
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Authors
Dates
2014-01-20—Published
2011-03-03—Filed