METHOD OF OBTAINING RUTIN Russian patent published in 2014 - IPC A61K36/70 A61K31/352 B01D11/02 

Abstract RU 2505307 C1

FIELD: chemistry.

SUBSTANCE: method of obtaining rutin from vegetative mass of buckwheat includes the following stages: dried, crushed buckwheat is subjected to extraction with 70% ethyl alcohol, thickened, filtered, dried, purified from admixtures by means of organic solvents, dissolved, subjected to hot filtration, crystallised, with crushed vegetative buckwheat mass being before extraction subjected to uncoiling, extraction with 70% ethyl alcohol on boiling water bath, filtration and re-extraction with 70% ethyl alcohol, re-filtration, obtained alcohol extracts are concentrated on water bath under vacuum and dried, twice purified from admixtures by means of organic solvents, as organic solvents used are diethyl ester and ethylacetate. After crystallisation, re-crystallisation is carried out with hot 70% ethyl alcohol with hot filtering through paper filter, with further cooling until rutin crystals precipitate, filtration under vacuum and drying in the open air.

EFFECT: application of the claimed method makes it possible to obtain rutin with high degree of purification.

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RU 2 505 307 C1

Authors

Pavlovskaja Ninel' Efimovna

Gneusheva Irina Alekseevna

Polekhina Natal'Ja Nikolaevna

Solokhina Irina Jur'Evna

Gor'Kova Irina Vjacheslavovna

Dates

2014-01-27Published

2012-05-29Filed