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2 505 526

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(51)

IPC

C07C229/60(2006-01-01)

C07C227/04(2006-01-01)

(21) (22)

Application

2012126288/04, 2012-06-22

(24)

Start date

2012-06-22

(22)

Actual filing date

2012-06-22

(45)

Published

2014-01-27

(72)

Inventor

Azev Jurij AlekseevichCharushnikov Kirill AleksandrovichGibor Aleksej MikhajlovichMokrushin Vladimir StepanovichBakulev Vasilij Alekseevich

(73)

Holder

Federal'Noe Gosudarstvennoe Avtonomnoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Federal'Nyj Universitet Imeni Pervogo Prezidenta Rossii B.N. El'Tsina"

METHOD OF OBTAINING ANESTHESINUM Russian patent published in 2014 - IPC C07C229/60 C07C227/04

Abstract RU 2505526 C1

FIELD: chemistry.

SUBSTANCE: invention related to method of obtaining ethyl ether of n-aminobenzoic acid (anesthesinum) of formula , which possesses local anesthetic action and is semi-product in Novocain synthesis. Method lies in reduction of ethyl ether of n-nitrobenzoic acid with further separation of target product. Method is characterised by the following: to simplify technology and increase product quality reduction process is carried out with mixing in isopropyl alcohol in presence of Raney Ni catalyst under hydrogen pressure 2.0-4.0 atm and temperature 60-70°C.

EFFECT: method makes it possible to avoid formation of considerable quantities of by-products and obtain anesthesinum with high output.

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RU 2 505 526 C1

Authors

Azev Jurij Alekseevich

Charushnikov Kirill Aleksandrovich

Gibor Aleksej Mikhajlovich

Mokrushin Vladimir Stepanovich

Bakulev Vasilij Alekseevich

Dates

2014-01-27—Published

2012-06-22—Filed