FIELD: medicine.
SUBSTANCE: producing paracetamol involves the catalytic hydrogenation of p-nitrosophenol with Pd/C or Ni-Re catalysts at 20-70°C in a combination with acetylation in aqueous ethanol or aqueous isopropanol in the presence of acetic anhydride.
EFFECT: advanced method for producing p-acetylaminophenol using inexpensive solvents and ensuring a high product yield.
6 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PRODUCING PARACETAMOL | 2011 |
|
RU2461543C1 |
| METHOD OF PRODUCING n-ACETYLAMINOPHENOL | 2012 |
|
RU2495865C1 |
| METHOD OF THE PRODUCTION OF PARA-ACETYLAMINOPHENOL | 2022 |
|
RU2800098C1 |
| METHOD AND APPARATUS FOR PRODUCING PARACETAMOL FROM PHENOL | 2023 |
|
RU2814270C1 |
| METHOD AND APPARATUS FOR PRODUCING PARACETAMOL FROM PARA-NITROSOPHENOL AND/OR PARA-NITROPHENOL IN ACETIC ACID MEDIUM | 2023 |
|
RU2818763C1 |
| METHOD OF PHENACETIN OBTAINING | 2012 |
|
RU2546111C2 |
| METHOD OF PRODUCING P-AMINOPHENOL AND DEVICE FOR PRODUCING P-AMINOPHENOL USING THIS METHOD | 2023 |
|
RU2822065C1 |
| METHOD FOR PRODUCING PARACETAMOL | 2016 |
|
RU2668500C2 |
| METHOD FOR PRODUCING PARA-AMINOPHENOL AND ZINC ACETATE BY REDUCTION OF PARA-NITROSOPHENOL WITH METALLIC ZINC IN ACETIC ACID MEDIUM | 2023 |
|
RU2798466C1 |
| METHOD OF OBTAINING ANESTHESINUM | 2012 |
|
RU2505526C1 |
