BIOMARKERS APPLICABLE FOR DIAGNOSING HEPATIC FIBROSIS Russian patent published in 2014 - IPC G01N33/68 G01N33/53 A61K39/395 

Abstract RU 2505821 C2

FIELD: medicine.

SUBSTANCE: invention refers to diagnostic techniques for hepatic fibrosis in an individual involving urokinase plasminogen, matrix metalloproteinase 9 and β-2-microglobulin expression tests to derive a score and to diagnose. Also, the present invention refers to a diagnostic kit for hepatic fibrosis comprising a first antibody specifically bound to an urokinase plasminogen activator (uPA), a second antibody specifically bound to matrix metalloproteinase 9 (MMP9) and a third antibody specifically bound to β-2-microglobulin (β-2-MG).

EFFECT: higher diagnostic accuracy.

17 cl, 33 tbl, 3 ex

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Authors

Tseng Tsu-Ling

Li Khong-Ji

Li E-Reng

Li Angelina Khuehj-Lo

Liu Ji-Chen

Cheng Ping-Fu

Lin Vej-Ja

Jekh Khong-Zen

Dates

2014-01-27Published

2009-12-01Filed