METHOD FOR PREPARING VACCINE OF LIVING NEMATODE LARVAE OF SPECIES Trichinella Railliet (1895) FOR IMMUNISING ANIMALS AND HUMANS, USING MILK OF ANIMAL IMMUNISED BY THIS VACCINE AS AGENT FOR PREVENTION AND TREATMENT OF IMMUNE DISORDERS, METHOD FOR PREPARING BLOOD SERUM OF IMMUNISED ANIMALS, AND METHOD FOR PREVENTION AND TREATMENT OF IMMUNE DISORDERS USING THIS SERUM Russian patent published in 2014 - IPC A61K35/00 A61K39/395 A61P37/00 

FIELD: medicine.

SUBSTANCE: group of inventions relates to biotechnology. A method for preparing the vaccine provides crossing of two different species of the four: T.spiralis, T.nativa, T.pseudospiralis and T.britovi, and selecting the line having the lower pathogenic and higher immunogenic properties by infecting with murine Trichinella larvae and controlling the embryogenesis; 1.5-2 months later, infected mouse's muscular tissue is separated, and the invasion larvae are recovered to be used for re-infection in a dose of 200-300 larvae; a degree of infection is determined, while the vaccine is prepared of the Trichinella line that leads to a mildest disease, while the re-infection causes no disease. Milk of the animals immunised with the vaccine prepared as described above is used for the purpose of prevention and treatment of the immune disorders. The vaccine described above is also used to prepare the serum. The vaccine is orally administered in a dose of 5000 to 20000 living larvae starting from the 10-14th day from the administration of the preparation; a usual therapeutic correction is required as that for trichinellosis, while the blood is sampled 30 days after the administration of the preparation. The prepared serum is administered into an individual according to the following schedule: either orally starting from 0.05 ml per one intake 3 times a day and increased to 1.2 ml by adding 0.05 ml to each intake, and then decreased in reverse order, or in the form of injections parenterally in a dose of 1-2 ml every 2 days, and in a dose of 10-15 ml into an animal three times to prevent and treat the immune disorders.

EFFECT: using the inventions described above enables more effective prevention and treatment of the immune disorders.

4 cl, 9 ex