FIELD: chemistry.
SUBSTANCE: invention relates to biotechnology and specifically to production of human pancreatic polypeptide analogues and can be used in medicine. The disclosed analogues differ from native human pancreatic polypeptide by replacement of amino acids on one or more residues, wherein position 0 is provided with an additional amino acid which is Gly.
EFFECT: obtained analogues provide effective treatment and prevention of obesity or diabetes in a patient, and can also be effective in reducing appetite, reducing food intake or reducing calorie intake in a patient.
26 cl, 2 dwg, 2 tbl,1206 ex
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